Korean Order Bride

Human Male Sex: Endocrine Disruption and Male Reproductive Wellness

Posted by on Feb 12, 2020 in Korean Order Bride | Leave a comment

Human Male Sex: Endocrine Disruption and Male Reproductive Wellness

9.1 Introduction

Male sexuality is determined genetically during the time of fertilization because of the existence of a Y chromosome within the spermatozoan since it fuses using the X-chromosome-containing ovum, plus the sex-determining area for the Y chromosome (SRY) then drives the bipotential gonad for the embryo to be a testis through hormone-independent mechanisms 1,2. Nevertheless, after the very early testis is created, growth of the total male phenotype, including further testicular development (masculinization), becomes totally determined by a complex system of hormonal signals, especially hormones secreted through the testes 2. People who lack any gonads are phenotypically female 1 and endocrine intervention is needed to change the standard feminine phenotype to be male 2. This will make both development and upkeep of masculinization at risk of endocrine-disrupting impacts after all developmental phases from very very early embryo to adulthood; in specific, interruption of very very early embryonic developmental processes might have consequences for male reproductive health in adult life 2.